Filya Ivanivna Zhebrovska was elected the General Director and Chair of the Management Board of Farmak JSC.
Since then, the mainstream of the Company’s activity was radical refocusing on production of competitive products complying with Good Manufacturing Practices (GMP). The Company started retrofitting activities: the first production line for drops under the Bottelpack technology was purchased and installed. The first product produced on the new production line was Naphthyzin.
Production of deficit ophthalmic medicines, antibiotics, medicines in the form of ointments was launched.
In late 1990-ies, Farmak signed an agreement for long-term partnership with the US corporation Eli Lilly, which is the leader in insulin development and production. The Company launched production of human rDNA insulins from the drug substance under the US partner’s licensed technology.
In 1996, the production output increased by 157.7 % as compared to that of the preceding year, while the quantity of products of the Company’s portfolio tripled over the period of 1995-1999.
Production of L-thyroxine was launched. Construction of a new tablet production facility certified according to the GMP rules was complete.
The medicinal product Amizon was developed in cooperation with scientists of the Pharmacology and Toxicology Institute of the Academy of Medical Sciences of Ukraine and the Organic Chemistry Institute of the National Academy of Sciences of Ukraine; commercial manufacture of the product was launched.
17 thousand square meters of new production facilities and 6 thousand square meters of administrative facilities were commissioned over 10 years.
One new production was launched each year since 2000. In 2001, colossal construction of the Finished Medicinal Product Workshop (FMP-1) was started. Foreign partners were engaged to the design, which was the first experience in the Ukrainian pharmaceutical industry. Thanks for this engagement, 4 production lines of FMP-1 were certified for the European market.
In mid-2000-ies, Farmak started opening its representative offices in other countries.
Today, the staff of Farmak’s representative offices includes about 200 experts.
In 2007, production of Magnegita® was launched, which is a generic product to the original contrast agent Magnevist® (gadopentetate dimeglumine). Farmak managed to be the first to synthesize the substance and to develop the finished dosage form as well as to prepare a registration dossier and to obtain authorization of the first generic of the original gadopentetate indicated for the use for magnetic resonance imaging in 22 countries of the European Union under the decentralized procedure.
In December 2010, Farmak commissioned the first stage of the large project entitled ‘SLM-2’ (Sterile Liquid Medicines), which includes two aseptic production lines for injectable products.
In 2000-ies, Farmak was proactive in colossal construction: the second stage of the Bottelpack production line (2010), production lines for liquid medicines (2007-2010), production facilities for dragées (2011) and soft gelatine capsules were launched over a short period of time. Full retrofitting of the manufacturing sites was complete in 2013.
In 2010, Farmak was recognized as Top #1 Company among domestic manufacturers having moved 4 positions up in the rating over 4 years and has surefootedly asserted the leadership to this day.
The Company obtained GMP certificates for all its production lines.
A new laboratory and process complex committed to research and development was launched.
The laboratories were equipped with cutting-edge equipment of such global manufacturers as Glatt, SBM, Urlinski, Belimed, De Ditrich, Gea, Sartorius, Malvern Instruments.