Two is a company, however three is not a crowd

The Ukrainian researchers have made it possible for the children, who previously had no chance for existing, to be born

Approximately every tenth couple in our country has certain problems in the reproductive sphere. But, fortunately, the technology of assisted reproductive medicine has been available and has successfully applied in the world for more than 40 years. “Test tube babies” are born, they grow, go to school and in their time give birth to their own children, of course, if they want. They are not different from the people who are conceived traditionally.

Assisted reproductive technology itself is constantly improving and becoming more efficient. But about 3 of 100 young women, who come to specialized clinics, face with an unsolvable problem: in the first days after fertilization, their embryo stops growing or developing properly. It is possible to change the clinic, to go to another country, to pay more, but it will not change anything – they will have no children.

Embryologist Pavlo Mazur from the private Kyiv Clinic of Reproductive Medicine “Nadiia” is one of the first people in the world who solved this problem and is the first who used this new technology. We discussed with him the issue how the “children from three parents” are born.

Hunting for Pneumocyst

The story of one important diagnostic test system which the Ukrainian researchers had developed before the notion became trendy. But it changed nothing.

In recent months, the phrase “test system” has become very popular due to the COVID-19 epidemic. There has been much talk around such issues: Can our researchers develop a diagnostic test system? How soon? Will it be high-quality as compared with foreign analogues? etc.

We decided to tell the story of a domestic diagnostic test system development. It has nothing to do with the diagnosis of coronaviruses and the diseases they cause. But it helps better understand the real attitude towards science in our country and answer a question that the community likes to put to researchers: “Where are your results?”.

Heart attack! To cancel!

The way the Ukrainian researchers are working to develop a new method for treatment of myocardial infarction consequences.

Globally, myocardial infarction is one of the leading causes of death. According to the WHO, cardiovascular diseases annually kill about 17 million people. 85% of the deaths are caused by heart attack or apoplectic attack. With regard to Ukraine, about 40 thousand myocardial infarctions are detected annually. The “mechanism” of this disease is activated by the “blockage” at some spot of a vessel which provides blood to the heart muscle. The cells are left without oxygen, and the organ cannot function normally. This happens very quickly, but if during the first hours after the attack the patient is delivered to the cardiovascular care unit, where they are rendered the necessary assistance, the negative effects for the heart will be minimal.

Otherwise, irreversible processes will take place very fast: part of the heart muscle cells (cardiomyocytes) die without oxygen. If the person survives, such cells are replaced by other connective tissue cells (fibroblasts). In lay terms, the heart forms a scar. It is evident that the heart cannot function properly as it did before with this scar, and modern medicine knows no methods how to get rid of it. Approximately every second person with such a “scar” in the heart will live with a disability.

However, in different countries the researchers are trying to develop various treatment modes of myocardial infarction consequences. Today one of these new approaches is being developed by the research group from the Institute of Molecular Biology and Genetics (IMBG) of the NAS of Ukraine under the leadership of Doctor of Biological Sciences Oksana Piven.